Marla Ahlgrimm on Systemic Inflammation

Systemic inflammation is a body-wide immune response that persists beyond its intended purpose. Marla Ahlgrimm explains that unlike acute inflammation, which is short-term and localized, systemic inflammation involves ongoing activation of immune pathways throughout the entire body. Over time, this can affect multiple organs and contribute to disease development.

Marla Ahlgrimm notes that inflammation is a protective mechanism. When the body detects harmful bacteria, injury, or toxins, the immune system releases signaling molecules called cytokines. These trigger increased blood flow and recruit immune cells to the affected area. The goal is tissue repair and recovery. In healthy cases, inflammation resolves once healing is complete. However, in systemic inflammation, that “off switch” becomes impaired.

Systemic inflammation occurs when inflammatory signals remain elevated in the bloodstream. This creates a low-grade but persistent immune response that can gradually damage healthy tissue. Instead of serving as a targeted defense, the immune system becomes overactivated. This can disrupt normal metabolic, cardiovascular, and neurological function.

What Causes Systemic Inflammation

According to Marla Ahlgrimm, there is no single cause of chronic inflammation. It typically develops from multiple overlapping factors, including autoimmune disorders, excess body fat, a diet high in ultra-processed foods, chronic psychological stress, smoking, alcohol use, untreated medical conditions, and a sedentary lifestyle.

Signs And Symptoms

Systemic inflammation often presents with subtle symptoms that are easy to overlook. Marla Ahlgrimm notes that common signs include persistent fatigue, muscle or joint discomfort, brain fog, bloating, irregular bowel movements, and frequent minor illnesses. Many people also experience generalized body aches that they may attribute to overwork or aging.

A chronically inflamed body does not always produce dramatic symptoms, especially in the early stages. Instead, Marla Ahlgrimm explains that individuals may notice a slow progression of symptoms. Even routine lab tests may not detect chronic inflammation unless specific inflammatory markers are measured.

Health Risks

Marla Ahlgrimm states that ongoing inflammation can contribute to structural and functional changes in tissues and organs. Chronic systemic inflammation may increase the risk of or worsen several major diseases, including cardiovascular disease, type 2 diabetes, neurodegenerative disorders, and certain cancers. It also plays a key role in many autoimmune conditions, where the immune system mistakenly targets healthy tissue.

What You Can Do

Marla Ahlgrimm emphasizes that chronic inflammation can often be addressed through a proactive approach. She recommends first speaking with a healthcare provider to evaluate any underlying medical conditions that may be contributing.

She also highlights lifestyle changes that can help reduce inflammation, including eating a diet rich in whole foods and healthy fats, engaging in regular physical activity, managing weight to reduce visceral fat, and maintaining consistent, high-quality sleep.

Ultimately, systemic inflammation is not a disease itself but a chronic state that increases the risk of many other conditions. It reflects a sustained imbalance in immune activity that can quietly but significantly affect nearly every system in the body. Marla Ahlgrimm encourages women concerned about chronic inflammation to discuss their symptoms and risk factors with their healthcare team.

Women’s Hormones and Muscle Mass | Marla Ahlgrimm

Hormones play a central role in shaping a woman’s muscle mass, strength, and overall body composition. While nutrition and exercise matter, these chemical messengers often determine how effectively the body can build, maintain, or lose muscle. Marla Ahlgrimm explains that understanding these influences can help us understand why muscle development feels easier at some stages of life and more challenging at others.

Estrogen

Estrogen is one of the most influential hormones when it comes to muscle health. It supports muscle repair, reduces inflammation, and helps maintain muscle quality. It also has a protective effect against muscle damage, which means women often recover differently from workouts compared to men. Marla Ahlgrimm says that during reproductive years, when estrogen levels are more stable, many women experience better muscle tone and recovery.

Estrogen levels naturally fluctuate throughout the menstrual cycle. In the first half, rising estrogen can support strength and performance, making it a more favorable time for intense resistance training. In the second half, progesterone increases and can offset some of estrogen’s benefits. This can lead to fatigue, reduced performance, and slower recovery. Marla Ahlgrimm notes that these shifts are subtle but can impact consistency over time.

Testosterone & Growth Hormone

Testosterone, although lower in women than in men, is still crucial for muscle development. It supports protein’s ability to rebuild. Women with relatively higher natural testosterone levels might find it easier to gain strength. Marla Ahlgrimm points out that even small variations within the normal range can influence training outcomes.

Growth hormone is another key factor. It works with insulin-like growth factors to support muscle repair and regeneration. It is released during deep sleep and after intense exercise. Poor sleep or chronic stress can reduce its production. Marla Ahlgrimm consistently stresses the role of sleep quality in muscle maintenance and overall health.

The Stress Hormone, Cortisol

Cortisol, the primary stress hormone, has the opposite effect. While necessary in small amounts, chronically elevated levels can break down muscle tissue and interfere with recovery. High stress, lack of sleep, and overtraining all contribute. According to Marla Ahlgrimm, managing stress is just as important as training itself.

Insulin

Insulin also plays a direct role by helping move glucose and amino acids into muscle cells. When insulin sensitivity is high, nutrients are used efficiently for muscle growth. When resistance develops, muscle building becomes less efficient and fat storage can increase. Marla Ahlgrimm notes that diet and activity levels strongly influence this process.

Hormones Through the Stages

Life stages bring significant hormonal shifts. During pregnancy, the body often prioritizes fat storage over muscle gain. After childbirth, rebuilding muscle depends on sleep, nutrition, and hormonal balance. Marla Ahlgrimm cautions women to set realistic expectations during this phase.

Perimenopause and menopause mark one of the most significant transitions. As estrogen declines, muscle mass and strength often decrease, a process known as sarcopenia. This is typically paired with increased fat storage, especially around the abdomen. Strength training becomes more important here, helping offset these changes. Marla Ahlgrimm underscores that this stage requires intentional adjustments, not less effort.

Final Thoughts

Hormones are not a barrier but a variable to work with. Aligning training, nutrition, and recovery with hormonal patterns improves outcomes. Prioritizing protein, managing stress, getting consistent sleep, and maintaining strength training all support a healthier hormonal environment. Muscle mass is not just about appearance. It supports metabolism, bone health, and long-term function. Marla Ahlgrimm stresses that understanding how hormones influence muscle allows for a more effective approach to strength at every stage of life.

How Sweet It Is (To Stop Sugar) | Marla Ahlgrimm

We all need a sweet treat every once in a while, but there are plenty of evidence-based health benefits of reducing refined sugars, such as desserts, processed snacks, and high-fructose corn syrup. Today, Marla Ahlgrimm shares the top 10 reasons that sugar should be used sparingly.

Reducing your sugar intake reduces glucose spikes.

Refined sugars can cause a rapid spike in your blood glucose levels. This is followed by an insulin surge, which can leave you feeling drained and lethargic. Marla Ahlgrimm notes that these rapid increases in glucose and insulin also increase your risk of type 2 diabetes, so quitting sugar can reduce your risk of this disease.

It’s easier to lose fat.

Once we reach the age of perimenopause, losing weight isn’t always easy. Marla Ahlgrimm explains, however, that we often thwart our own efforts by our snack choices. Reducing your sugar intake can naturally reduce your overall caloric intake. As a result, you may notice less fat in your abdomen, feelings of being more satisfied after eating, and more energy.

Lower inflammation levels.

If you suffer from systemic inflammation, lowering your sugar intake can help reduce it. Marla Ahlgrimm notes that eating less sugar can also improve joint discomfort and support immune function.

Your heart will thank you.

Excess refined sugars increase triglycerides and blood pressure. By lowering your intake, you reduce these risk factors that contribute to heart disease and other health concerns.

You’ll reduce your risk of fatty liver disease.

Fatty liver disease warrants a mention on its own, as this condition is often made worse by consuming sweetened beverages, including sugary coffee and soft drinks. Marla Ahlgrimm explains that cutting sugar reduces liver fat accumulation and can improve enzyme markers.

Energy will come naturally.

If you typically consume a sugar-laden drink or snack as a pick-me-up, you should know that reducing your sugar intake overall can lead to stable and long-term energy. In other words, Marla Ahlgrimm says you won’t experience the crash or the mid-afternoon slump that can lead to brain fog and lethargy.

Cravings may go away.

There’s no easy way to say this: sugar is a drug. Marla Ahlgrimm says that sugar activates your brain’s dopamine reward pathways and makes you look at food, specifically sugar, as a quick way to get a dopamine hit. By eliminating refined sugars, you’ll reduce your craving for sweets and improve your appetite regulation.

Glowing skin.

In our 40s and 50s, our skin can begin to really show the signs of aging. Reducing your sugar intake slows damage to collagen and elastin, two of the main compounds in our face that keep our skin smooth and supple. By cutting out sugar, you’ll decrease the rate at which your face ages.

Improved oral health.

Marla Ahlgrimm says that one of the damaging ways sugar can affect a woman’s health is by causing enamel erosion and cavities. Further, eating too much sugar can make it harder to maintain healthier gums, as it feeds oral bacteria. By cutting out sticky, refined sugars, you can improve your oral health and keep your teeth pearly white.

Better hormone function.

For women in their menopause era, improved hormone balance may be the number one reason to quit sugar. Marla Ahlgrimm says that by reducing your sugar intake, your body may regulate its cortisol levels, and this can result in improved PMS symptoms and a reduced risk of conditions such as PCOS, which are insulin-driven.

You don’t have to deprive yourself completely. Marla Ahlgrimm says that reducing your sugar intake does not mean cutting out everything you love. She does recommend, however, finding healthier ways to satisfy your sweet tooth. Doing so can help you experience all of the benefits above and more.

Marla Ahlgrimm on How Subtle Hormone Changes Affect Women’s Health

As women, we’re used to how our hormones can play a role in our everyday health and well-being. But, according to Marla Ahlgrimm, even minor hormone fluctuations can affect everything from mood and sleep to energy and even how our bodies react to outside influences.

Marla Ahlgrimm explains that hormones influence nearly every major system in the body. However, most women are taught from an early age to only pay attention to the “big” hormonal shifts, which typically happen around puberty, pregnancy, and menopause. In reality, even small hormone variations between these periods of life can have a noticeable effect on how we feel each day. Even changes that fall within “normal” lab ranges can still affect energy levels, stress tolerance, sleep quality, mood, and other aspects of our lives.

Hormones Work In Balance

One of the most important things women should know is that their hormones work in balance. Marla Ahlgrimm likens this to a symphony rather than a solo performance. Estrogen, progesterone, thyroid hormones, cortisol, and more interact constantly. Even a slight drop in one of these can influence how the others behave. Because of this, Marla Ahlgrimm says that symptoms of health conditions can appear before any of the levels of these hormones are considered abnormal.

Small fluctuations are triggered by the menstrual cycle, stress levels, sleep changes, caloric intake, illness, inflammation, aging, and medical changes. Marla Ahlgrimm also notes that hormone changes can be affected by a woman’s physical activity. And while small fluctuations are considered normal, they are not always without symptoms.

Mood Changes Begin With Small Shifts

Even mild hormone variations can influence neurotransmitters in the brain. Estrogen and progesterone especially affect serotonin, dopamine, and other chemicals that regulate mood and emotional stability, says Marla Ahlgrimm. A subtle swing up or down in any of these can show up as irritability, anxiety, and an overall roller coaster of emotions.

Sleep Matters

Marla Ahlgrimm explains that our hormones are highly sensitive to our sleep patterns, and sleep quality is also affected by hormones. Progesterone has a calming and sleep-supporting effect. Cortisol controls the sleep and wake rhythm. Estrogen regulates body temperature and the sleep cycle. Marla Ahlgrimm notes that small disruptions can lead to night waking, lighter sleep, and feeling unrefreshed despite having spent the recommended seven to nine hours technically asleep.

Energy Levels And Hormone Rhythm

According to Marla Ahlgrimm, a woman’s energy level is one of the earliest indicators of a subtle hormone shift. Hormones regulate how each cell uses the fuel it’s provided, how the thyroid controls metabolism, and even how the body processes blood sugar. An insignificant “on paper” shift in hormone levels can leave a woman feeling wiped out in the afternoon, mentally fatigued, and physically energetic but out of it.

Supporting hormone stability

Marla Ahlgrimm says that it doesn’t matter what age or stage you are in; fluctuating hormones can take a toll on your daily routine. She explains, however, that there are a few self-help steps that you can take to support hormone stability each day. This includes maintaining a consistent sleep schedule, eating meals that are high in protein and fiber, working out, eating enough calories, reducing alcohol and caffeine consumption, and getting enough daylight. The retired pharmacist and women’s health expert explains that these small steps can help smooth out the hormone rhythm so that dips may not be quite as noticeable.

Ultimately, Marla Ahlgrimm reports that hormone health is not just about major life stages. Small routine fluctuations that are considered clinically insignificant can have a huge effect on our daily lives. Recognizing the patterns can give women more insight into our bodies and more control over our well-being each day.

Love And Marriage (And Women’s Health!) | Marla Ahlgrimm

Marriage and meaningful relationships play a powerful role in a woman’s overall well-being. While independence and self-growth are essential, humans (and women in particular) tend to thrive when they feel emotionally supported, seen, and connected. According to Marla Ahlgrimm, strong relationships are not a luxury for women but a biological and emotional need that directly affects mental, emotional, and even physical health.

Research consistently shows that women in healthy marriages or long-term partnerships often experience lower stress levels, better immune function, and greater life satisfaction. Marla Ahlgrimm emphasizes that the key factor is not marriage itself, but the quality of connection within it. A supportive partner can serve as a buffer against life’s pressures, offering emotional safety and stability that allows a woman’s nervous system to relax.

Emotional intimacy plays a significant role in hormone balance. When a woman feels secure in her relationships, her body produces less cortisol, the stress hormone, and more oxytocin, often called the bonding hormone. Marla Ahlgrimm explains that oxytocin is essential for emotional regulation, sleep quality, and even metabolic health. Over time, chronic loneliness or relational stress can disrupt hormonal rhythms and contribute to anxiety, fatigue, and inflammation.

Marriage can also encourage healthier behaviors. Women in stable relationships are more likely to attend medical appointments, maintain routines, and prioritize rest. Marla Ahlgrimm points out that shared accountability within relationships often leads to better long-term health outcomes, especially as women age. Having a partner who notices changes, offers encouragement, or simply shares daily life can make a meaningful difference.

That said, not all relationships are beneficial. Marla Ahlgrimm is clear that unhealthy or emotionally unsafe marriages can do more harm than good. High conflict, lack of respect, or emotional neglect can elevate stress hormones and negatively affect mental health. This is why relationship quality matters more than relationship status. A peaceful single life can be healthier than a stressful partnership.

Beyond marriage, friendships and family relationships also play a critical role in a woman’s wellbeing. Marla Ahlgrimm often reminds women that community matters. Close friendships provide emotional outlets, validation, and joy, all of which support psychological resilience. Women who maintain strong social ties tend to cope better with life transitions, grief, and aging.

As women move through different stages of life, from motherhood to midlife and beyond, relationships become even more important. Marla Ahlgrimm notes that during hormonal shifts such as perimenopause and menopause, emotional support can significantly reduce feelings of isolation. Feeling connected helps women navigate change with greater confidence and stability.

Ultimately, marriage and relationships are not about dependence, but about partnership. Marla Ahlgrimm teaches that healthy relationships allow women to be fully themselves while feeling supported, understood, and valued. When a woman experiences consistent emotional connection, her body and mind respond positively.

In a culture that often glorifies self-sufficiency at all costs, it is important to remember that connection is not weakness. As Marla Ahlgrimm reminds us all, relationships are foundational to a woman’s well-being. Whether through marriage, friendship, or community, meaningful relationships help women live healthier, fuller, and more emotionally balanced lives.

Empty Nest Syndrome: Marla Ahlgrimm

For many women, the perimenopause and menopause years come with more than just a changing body to worry about. Marla Ahlgrimm says that there is a significant emotional shift that profoundly impacts many women’s health. What is it? An empty nest.

The time when a woman’s children are aging out of home and moving away to college or to begin their adult life is marked by freedom and opportunity. However, Marla Ahlgrimm says that it can also trigger feelings of loss, a change in identity, and increased stress, which manifest in physical and mental health challenges. It’s more than just a mental adjustment; it’s a stressful stage of life that initiates often unwelcome psychological changes.

The Absence of Children

According to Marla Ahlgrimm, the empty nest stage is about more than just the absence of children. She explains that many moms experience a swift disruption of their daily routine and what they may view as a downgrade in their primary role as a parent and provider. Women often live their lives revolving around their children from birth until 18 to 20 years old. Marla Ahlgrimm says this includes managing schedules, helping with homework, and assisting her children in navigating everything from learning how to walk to experiencing their first broken heart. When that demand diminishes, women can experience a loss of purpose and a feeling of being unneeded.

Empty Nest Stress

It’s no secret that chronic stress elevates the production of the stress hormones cortisol and adrenaline. Marla Ahlgrimm says that the stress of living in an empty nest is no different. And, unfortunately, there are many physical ailments that women can experience as a result. These include changes to her cardiovascular health, immune system depression, sleep disturbances, digestive issues, and weight gain. Marla Ahlgrimm says that all of these are directly tied to increased levels of cortisol and adrenaline.

The Emotional Impact

All of these sudden changes to a woman’s life can lead to or exacerbate mental health issues. Marla Ahlgrimm says that women may, for example, have an identity crisis, as for the last two or more decades her identity has been entwined with her role as mom and caregiver. Depression and anxiety are also common, and her romantic relationships may even take a hit.

Reinvestment

As women learn to readapt to life outside of the role of mother of children, they must learn to reinvent and reinvest in themselves. Marla Ahlgrimm says that seeking support through a therapist or with other moms experiencing this same stage of life can help women process their grief and redefine their goals. Physical activity is also important, as it works as both a stress reliever and a way for the body to naturally regulate sleep. Marla Ahlgrimm insists that women may find great joy in new hobbies or even traveling, continuing their education, or prioritizing their careers.

Ultimately, women experiencing empty nest stress should acknowledge the reality of this role in life. While this may come at a time when she’s already dealing with physical changes thanks to ever-changing hormone levels, watching her children spread their proverbial wings and soar off into adulthood is not a time for dismay but rather an opportunity to celebrate the lives that she’s impacted and the young adults she’s prepared to take on the world around them.

© 2019 Marla Ahlgrimm. All Rights Reserved.